The crazy thing about iron overload is that it can/will cause inflammation. And also depletes vitamin C and other anti-oxidants. So I wouldn't be surprised if your CRP come back high. The best low-tech approach would be to start donating blood to reduce your iron stores. Giving blood is a healthy thing to do for men and post-menopausal women as long as they have enough to give. You just need to monitor your blood counts and FE. You can be very aggressive and do it weekly with close monitoring by your doc.

My husband has both....iron overload and high CRP. And since FE is an acute phase reactant, just about anything will cause it to spike when FE is already elevated.

Excess iron gets stored or deposited into other organs. This will not be picked up by blood tests. There are some places that can do a special MRI of the liver to detect excess iron deposits. The pancreas and heart are usually effected first.

You may want to check out www.ironoverload.org

Marlene