5-HTP is NOT a safe alternative to L-Tryptophan. L-Tryptophan metabolizes into 5-HTP but not without the brain's regulatory system controlling it.

5-HTP bypasses this regulatory system. 5-HTP can easily be overdosed and result in serotonin syndrome.

SAMe may be used by some for depression but it does not effect neurotransmitters like L-Tryptophan.

SAMe also needs to be only be taken with the appropriate Vit B and other supplements. Otherwise, it can cause a dangerous increase in homo-cysteine levels.

The L-Tryptophan controversy has long ago been resolved. It was an isolated incident due to manufacturing contamination.

As you can see, I am choosing to use a physician's assistance before attempting to fiddle with my brain's neurotransmitters.

I suggest others do the same.