Somehow I'm not very excited by the MJFF. I hope they do make some important contributions in the fight against PD but I wonder. I've tried in the past to bring their attention to low dose naltrexone, LDN, which many people take for MS but not very many with PD. One can go to the yahoo lowdosenaltrexone web site to see the thousands of anecdotal comments made for LDN but I prefer to believe in the research done at the NIH by Dr. Hongs Pharmacology group. They have produced many papers over the past 10 years on low doses of naltrexone, dextromethorphan and other similar compounds which have shown to greatly reduce over activated microglia (killer cells) in the brains of rodents. Over activated microglia are believed to be the latest cause of PD.
I have been taking LDN and Sinemet now for 5 years and 3 months. I still take a small amount of Sinemet and also a small amount of Mirapex. The overall mix has not been increased over this time. I now have ankle swelling and after reading the post here on Mirapex like drugs causing heart valve scarring, I now have something else to worry about. I have cut back recently on Mirapex on my own. I have a neuro apt. in 3 weeks, I wonder if she will own up to the potential disaster awaiting many of us.
So if anyone can get MJF to talk to Dr. Hong, I would be more positive about his foundation.
Ashley
http://www.fasebj.org/cgi/content/full/19/6/550
http://jpet.aspetjournals.org/cgi/content/full/304/1/1
http://jpet.aspetjournals.org/cgi/co...urnalcode=jpet