LOL, I am not a brainiac but I can say 18 years ago Plasma exchange helped me but I am a little confused as the having to go in through the neck, I had mine done through the arm, in fact I used to joke about it because they took the blood from one arm and was replacing it into the other and they charged me 300 to take it out and 300 to replace it, I hate see to what it would cost today