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Old 09-22-2009, 04:26 PM
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fmichael fmichael is offline
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Join Date: Sep 2006
Location: California
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fmichael fmichael is offline
Senior Member
fmichael's Avatar
 
Join Date: Sep 2006
Location: California
Posts: 1,239
15 yr Member
Default Outpatient ketamine: A controlled study

Didn't get around to opening Dr. Kirkpatrick's link/footnote regarding Dr. Schwartzman's upcoming article. My mistake:
OUTPATIENT KETAMINE: A CONTROLLED STUDY

In Press

"Outpatient intravenous ketamine for the treatment of complex regional pain syndrome: a double-blind placebo controlled study"

DREXEL UNIVERSITY COLLEGE OF MEDICINE

Robert J. Schwartzman, MD
Guillermo M. Alexander, Ph.D.
John R. Grothusen, PhD.
Terry Paylor RN
Erin Reichenberger MS
Marielle Perreault BS

This recent controlled study with low-dose ketamine in an outpatient setting demonstrated a statistically significant (p<0.05) reduction in many pain parameters.

http://rsdhealthcare.org/PatientInfo...t_ketamine.htm
Curious to see whether this study included any chronic CRPS patients, where Dr. Schwartzman's last published work on the subject suggested, in the 3 page discussion at the end, that "low dose" ketamine was most likely to have a beneficial effect (only) in fresh (or "acute") cases, as opposed to those with chronic CRPS, who were found to receive no significant benefit in the albeit open label "pilot study." A Pilot Open-Label Study of the Efficacy of Subanesthetic Isometric S(+)-Ketamine in Refractory CRPS Patients, Kiefer RT, Rohr P, Ploppa A, et al, Pain Med. 2008;9(1):44-54, full text at http://www.rsds.org/2/library/articl...ohr_Ploppa.pdf
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