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Old 09-25-2009, 05:03 PM
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reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default alpha lipoic acid plus acetyl-L-carnitine report

I think this is Day 3 of my experimenting with increased and more frequent dosing. It is turning into something very promising so I want to fill in a little background just in case it is important. I don't think it is, but want it on record in case I'm wrong.

A little over two weeks ago I started a similar trial with ginger extract thinking to tap into its many properties, particularly its anti-inflammatory actions and a reported ability to block MSG. As it turned out, it seemed to cause me some of the same problems as the nasty additive. After several days of increasing dyskinesia I quit it at the one week mark. Spent a week doing better each day. Decided to up the ALC/ALA dose to help things along. The effect was good enough to get my attention.

Today was the first one where I maintained reasonable self-discipline. My usual pattern has been to start the day with a sinemet 10-100 plus a sinemet cr 50-200. Then twohours later 8 mg requip. Two hours aftr that a single cr 50-200. Two hours later two requip. Repeat until dinner and then struggle through to bedtime.

Today began at 4 AM with a 10-100 and a cr 50-200 and 100 mg ALA plus 1 g ALC;

*Three* hours later I took 8 mg requip plus ALA/ALC and decided I would try the three hour spacing today;

10 AM took ALA/ALC but forgot the cr 50-200!!

10:30 realized my mistake as sensed off coming. Took one cr plus one 10-100.

Off for awhile but back on about 11:30 (when I posted). Had a half hour of moderate dyskinesia. Took nothing more until...

4:15 !!! And even then didn't feel the need. So I took half a cr 50-200 plus ALA/ALC.

It is now 5:45 and I feel fine! Normally by now I would have maxxed out meds at (1) 10-100; (3) cr 50-200s; and 24 mg requip; and be planning to cheat another dose to get me to bed. Instead I am at (2) 10-100; 8 mg requip; and (2.5) cr 50-200s! And that extra 10-100 was a fluke.

I'm light by 16 mg of darned requip and 100 mg of cr sinemet! Who'd a' thunkit??

Sensing the first hint of off,I'm going to add another half a cr and ALC/ALA and see what happens.
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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