I'm sorry to hear you are having such a hard time. I've had 17 or 18 infusions. I'm having to go off tysabri, but did have good results from it. I noticed improvement in about 4 mos. I also got back some feeling the Dr said I would never get back. I saw one woman go from a chair to a walker after her 1st infusion. I really think the results depend on the individual. I wish you well!