Quote:
Originally Posted by pegleg
The movement specialist that I see in Atlanta (Emory) says most doctors don't like Sinemet CR because of its "unpredictability." A CR 25/100 is about 1/4 stronger (levadopa) than a regular 25/100. For this reason many have worse dyskinesia when they use CR.
Try some of those ideas that Rick mentioned - I've been thinking about trying them myself. And we who are "seasoned" (I've had PD for 15+ years) know what we're talking about when we say not to wait until you are "off" to medicate.
Peggy
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I love how I always learn something new here! Peg, thanks for sharing what your neurologist told you about CR. I've been doing really well but this weekend things went a little wonky due to stress; I have found that the CR seemed less predictable in going on. Now that I think of it, my doctor did mention that there can be a "skipped dosage" phenomenon with it where it never kicks in until next one.
I didn't know that it had more levodopa in it? I had read that when changing from regular Sinemet to CR, that one had to actually increase their strength by like 15 % or so to account for slow release. I could be wrong. Anyone else have switching experience that may help?
Here's hoping that we get some relief through smoother, more even delivery of levodopa. How is that Duodopa trial going? Also heard we might eventually get a patch delivery?
Laura