Inquisit,

Welcome! I don't know if this is the same 'feeling' or not....but before Mestinon, I used to feel like a had 'little bugs' rapidly crawling under my skin. Not all the time, but when it happened it could literally make me think I had a 'little bug' crawling up my arm or leg and I would look quickly to brush it off!!

Anyway, it has stopped since I started Mestinon and we think the sensation was lymph moving. When my muscles weren't properly supporting my 'skin' lymph - I used to get a lot of 'puffiness'. Sometimes to the point of fibrotic swelling (that was treated with compression devices).

Anyway - ALL of that is gone (it took a few months) since Mestinon. Coincidence? Don't think so....my neuro told me to expect this when I was given my first script.

Sue