Quote:
Originally Posted by neurocitizen
I've had a myriad of tests after experiencing a small fiber-like neuropathy for the last year. The only thing that came out abnormal was a positive gliadin reading of 38.
My question is could I just have gluten sensitivity and not have Celiac? Are they different? I have no other symptoms. Thanks.
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As others have answered, YES, you can have gluten sensitivity causing neuropathy without having celiac disease.
I can direct you to the pages of the Gluten File that address these things specifically~ there you will find excerpts from various literature that supports the reality of gluten sensitivity causing neurological and other disease, without necessarily testing positive for celiac disease (which is the gut manifestation diagnosed by villous atrophy).
Here are a couple such excerpts... in addition to a gluten free diet also be sure you also have optimal levels of those vitamins important for nerve health! (pretty much anything that applies to celiac disease applies to gluten sensitivity, except the requirement of villous atrophy)
Quote:
"But the two things which are relevant to CD are nutrition and immunity. People with CD have nutritional deficits because of malabsorption; common causes of neuropathy are B12 deficiency, B1 deficiency, B6 deficiency, and Vitamin E deficiency. Neuropathies are also commonly caused by the immune system through autoimmune mechanisims."..."Latov commented that 20-25% of people with CD might have neuropathy."
Celiac Disease and Peripheral Neuropathy, Norman Latov, MD, PHD 2002
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Quote:
Gluten sensitivity as a neurological illness
http://jnnp.bmj.com/cgi/content/extract/72/5/560
M Hadjivassiliou, R A Grünewald, G A B Davies-Jones:
FROM GUT TO BRAIN
Gluten sensitivity is best defined as a state of heightened immunological responsiveness in genetically susceptible people.15 This definition does not imply bowel involvement. That gluten sensitivity is regarded as principally a disease of the small bowel is a historical misconception.28 Gluten sensitivity can be primarily and at times exclusively a neurological disease.29 The absence of an enteropathy should not preclude patients from treatment with a gluten-free diet.
Early diagnosis and removal of the trigger factor by the introduction of gluten-free diet is a promising therapeutic intervention. IgG antigliadin antibodies should be part of the routine investigation of all patients with neurological dysfunction of obscure aetiology, particularly patients with ataxia and peripheral neuropathy.
PERIPHERAL NEUROPATHY
Peripheral neuropathy is the second commonest manifestation of gluten sensitivity. Prospective screening of 101 patients with idiopathic peripheral neuropathy has shown the prevalence of gluten sensitivity to be 40% (unpublished data). The commonest type of peripheral neuropathy we encountered is sensorimotor axonal (26) followed by mononeuropathy multiplex (15), pure motor neuropathy (10), small fibre neuropathy (four) and mixed axonal and demyelinating (two). The neuropathy is usually chronic and of gradual progression. Patients with a pure motor neuropathy may progress to involvement of sensory fibres.
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More here:
http://jccglutenfree.googlepages.com...ationsofgluten
http://jccglutenfree.googlepages.com...eralneuropathy
http://jccglutenfree.googlepages.com/diagnostictesting
http://jccglutenfree.googlepages.com...niggantibodies
http://jccglutenfree.googlepages.com...sceliacdisease