You may think me crazy but I realized that when my MG was in remission I didn't have a urination problem but now that I am back on mestinon I have to "go" all the time! I remember when I was first DXed with MG I had a "going" problem then too, I don't know if it is the MG or the mestinon, but I have noticed that when I take the mestinon I have to go and go and go.