Sorry, this is going to be a little gross.

Mestinon increases acetylcholine. Acetylcholine increases muscle strength. Muscle strength increases peristalsis, which can cause increase in the number of stools per day or an increase in the runny consistency of stools (both considered diarrhea).

The bladder muscles may be overactive from the properties of the drug. Not much is written up about that. But weak muscles or those with too much acetylcholine can cause the bladder to "let loose." Muscles get weaker when you sleep and you can end up "wetting the bed" too.

Mestinon does not affect all muscles in an equal way. Just like a pain med may make that slight headache better but may not make the raging pain in someone's back better. Mestinon could be helping with breathing, etc. but maybe it's making the bladder muscles a bit too better. Meaning, they are "overdosing" on the Mestinon. Does that makes sense?

Anyway, whatever is causing this for you, I hope you get some relief from it.

Annie