Yes for sure TOS can cause flares and pain issues when you feel stable or somewhat good. All it takes for me could be one bad day doing too much cleaning or doing ironing always brings on flares. I have had remissions as well. My recent vacation in mexico caused remission......a week...maybe it was the tequila....who knows. So to answer your question it differs for all people but I think you will find most of us flare up and go into remission......

hope this helps
take care
hugs,
Victoria:icon_wink: