Dear Mslday -

Recalling our dscussion a couple of weeks ago in your Fear and Funtionality thread, http://neurotalk.psychcentral.com/thread103593-4.html, I would once again endorse the use of Zometa as the ONLY effective treatment I have have for the previosly debilitating "deep, bone crushing pain" in my feet. (Please see my Post No. 35.) That said, I recognize fully that you had a different experience with Pamidromate. (Post No. 33, above). Nervertheless, as set forth in my post, the two are different drugs with different risk profiles. I would strongly urge you to discuss the relative merits of Zometa with your physician.

A link the the FDA approved U.S. prescribing information sheet for Zometa is included in my prior post: please note that it bears little resemblance to the risks of Pamidromate to which you had referred/linked. Once again, only your physician is qualified to speak on whether a severe reaction on one drug would preclude trying the other.

And for what it's worth, I found out yesterday that my insurance company's prior objections to the use of Zometa were being overridden, and that I had the green light to proceed with further treatments, subject of course, to getting a clean bill of health on my kidney functions.

Mike