Hi I did take both for about a year and half. It helped me greatly. I no longer take them both and now take Cymbalta, Lyrica and Tramadol. It is a good combination for me. I also started IVIG for my neuropathy symptoms because I am at the point that I would like to decrease the Lyrica as I have gained so much weight. I just started the infustion therapy so time will tell. But, yes, Lyrica and Neurontin can be safely taken together and yes it can help the pain greatly.