Gene therapy for Parkinson's "encouraging" in early trials
October 15, 2009, 1:52pm
http://www.mb.com.ph/articles/224797...g-early-trials
PARIS, October 14, 2009 (AFP) - A gene therapy for Parkinson's disease that has been tested on lab monkeys is showing good early results in a small-scale trial on humans, French researchers said on Wednesday.
The therapy entails taking three genes that produce dopamine, a key neurochemical that is depleted in Parkinson's. The genes are then inserted into a disabled equine virus that is then injected into the brain.
Six human volunteers began clinical trials a year ago, and the results are "extremely encouraging," as measured in control of Parkinson's symptoms and in side effects such as brain inflammation, neurosurgeon Stephane Palfi told AFP.