we are so tired of hearing about gdnf. when will these researchers realize it's time to give it up?
NOT?? how about?
you encourage me and keep me going, it's not over till it's over. We need to stay current and speak to patients and doctors.
that's better. 
from the article,
"In fact, it has been proposed that the lack of glycosylation of the protein in the clinical trials of Parkinsonīs disease could be responsible for the appearance of anti-GDNF antibodies in 10% of the patients enrolled in the last phase II clinical trial (Lang et al., 2006), which was halted at least in part owing to safety concerns.
from pipeliner email:
"they state antibodies found in some of the gdnf trial participants may have been due to impure form of gdnf used."
paula