It is very possible for the treatment to be worse than the disease. I was on Avonex for 2-1/2 years and my symptoms kept getting progressively worse. Right before I stopped taking it, I could barely walk across the room and was in constant pain. I described it as my joints and muscles felt like they were on fire and melting. I skipped a shot and my symptoms started improving so I never looked back. That was in 2004 and my RRMS has been relatively stable.