I notice too that the symptoms they list are those we get with RSD anyway, so alot of folks would assume they were just getting worse not becomming intollerant to their medicine.. And the detoxification would/should be either temporary or until something else satisfactory could be found to adiquitly controll the pain in this case I would think anyway.

RSD/CRPS is not included in their patient's ailments in this study, and they do imply that the symptoms of hyperalgesia and allodynia are not symptoms they are expecting in their study participants.
I find their thoughts/supositions on hyperalgesia very interesting.
I become intollerant of most drugs before too long it seems, a very few I have been on for the long haul, such as baclofen.
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JimKing, Hi there..

Yes the ibuprophen is not good for the stomach and heart after very long either, not to mention that it is usualy not enouph pain relief for us, though it helps with the achey pain.. it does nothing for the deep bone pain or the various other types of pain thet RSD folk get.. for that we need an assortment of meds for each symptom.. I too have found that is the best way to manage this beast.

Best wishes,
S