I'm with Debbie...I've been taking Naproxen twice a day for...um, forever, I guess. Just yesterday my doctor reminded me that I was taking the "recommended dose" (in other words, as much as I can) and there are times that I'd sell my inheritance for an extra dose.

I've had arthritis longer than I've had MS symptoms, but for me it's a moot point whether or not the Naproxen is contributing to the fatigue. If awake means sitting there watching my ankle throb, I'd just as soon be asleep.