thanks for the input. There are a lot of other symptoms to lead to a lupus diagnosis i am afraid. Gave the ANA issue to all 3 of my kids. one just tested 1:640 - I am really scared. the PN was one thing to deal with, now i have constant headaches, severe eye pain, fatigue and a bunch of other wonderful side effects. seeing rheumy in nyc on monday, but primary and neuro thinking lupus. not sure what i have ahead of me, never mind what i have given my kids.