Hi cat265,

I'm glad your doctor suggested you try a gluten free diet. Although your biopsy was negative, there are many many many cases of people who improve miraculously on a gluten free despite lack of a celiac diagnosis.

This comes down to the difference between gluten sensitivity and celiac disease. Celiac disease, by definition, requires villous atrophy. But, you can be gluten sensitive and have other related disease, such a dermatitis herpetiformis (skin manifestations) or gluten ataxia, or many other wide ranging symptoms, without showing villous atrophy. Gluten sensitivity that doesn't show as celiac disease (villous atrophy) has been a somewhat controversial subject for years, but science is finally beginning to back up what patients have known for decades... gluten causes problems for many who don't meet the diagnostic criteria of celiac disease. And, it may be relative in other autoimmune disease, as well.
http://jccglutenfree.googlepages.com...sceliacdisease
http://jccglutenfree.googlepages.com/zonulin

A positive antigliadin IgG does suggest you are gluten sensitive and will likely benefit from a gluten free diet. Left untreated, you may eventually progress to show villous atrophy. But, there are also those who will never show villous atrophy, but are symptomatic, and do respond to a gluten free diet.

The antigliadin IgA antibodies are more associated with a damaged gut, whereas antigliadin IgG may be more suggestive of non-gut manifestations..... but that is just a generality. My daughter had only a mildly positive antigliadin IgG, yet she had major gut symptoms, neurological symptoms and skin symptoms... and they all resolved on a gluten free diet.

I'm not sure what all of your symptoms are, but gluten sensitivity can cause wide ranging neurological symptoms (neuropathy, ataxia, white matter lesions, seizures, myopathy, and more), gastrointestinal symptoms, skin symptoms, can affect essentially any organ/tissue in the body, and is associated with several autoimmune diseases. If you have any symptoms at all, I'd definitely recommend a gluten free diet. About half of those with gluten sensitivity also have sensitivity to casein (cow's milk protein).


I'm not sure what this means~
Reticulocytes CGr 35.0 ref. range 25-30.
but here is the labtestsonline link for it:
http://www.labtestsonline.org/unders...te/glance.html