for some reason, many physicians are not aware of the fact that the time of the day in which you take your pred. is very important, and don't adress this at all.

we normally have what is called a diurnal rythym. the highest amount of cortisone is during the early morning hours, and that is when our body "expects" to have the highest level. so if you take your pred. during those hours, it may decrease your side-effects significantly.

alice