NeuroTalk Support Groups - View Single Post - Is this the end of the road? any final suggestions?

Kiwiboy · 11-03-2009, 09:33 PM

Quote:

Originally Posted by glenntaj

--certain types of small-fiber syndromes are very hard to find. In fact, in my case, the ONLY test that was abnormal and revealed that there was a reason for feeling the burning all over my body that I was having was the abnormal skin biopsy which showed significant reduction in intrepidermal nerve fiber density.

You should take a look at:

http://www.thecni.org/reviews/13-2-p07-treihaft.htm

--which is an excellent article about small-fiber neuropatheis and the difficulty of diagnosing them.

I'd also look through the Liza Jane spreadsheets, which are lists of tests for neurological problems (with the abiliyt to track results over time, to look for patterns), and the Poncelet and Latov testing protocols:

www.lizajane.org

http://www.aafp.org/afp/980215ap/poncelet.html

http://www.questdiagnostics.com/hcp/...eralNeurop.htm

Once again, Thank you Glenn. I have read through that information. The following passage I found of interest/hopeful. Maybe I'm in the 'second group'?
"Two distinct clinical patterns emerge based on the spatial distribution of symptoms and the IENF studies. The majority of patients present with progressive peripheral dysesthesias and distal fiber loss consistent with a length dependent or dying back process. A second smaller group of patients experience a monophasic illness characterized by the acute onset of generalized cutaneous burning of the limbs and trunk followed by slow recovery. In this group, IENF studies reveal generalized small fiber loss without the proximal-distal gradient. These findings suggest direct involvement at the dorsal root ganglia

How does one tell if something is 'monophasic' is it a matter of wait and see? That it said, 'followed by slow recovery' seems like a glimmer of hope? But in saying that, the pain in my hands I suppose is presenting in 'distal' manner, but then the burning is without the proximal-distal gradient? and there is no more toxic exposure so I guess anything is possible...I guess whether it might be probable is the question.