I have been experimenting with coffee and I think that one cup of coffee or tea replaces about 15 mg of Mestinon for me. I have to be careful with caffeine or I get twitchy muscles. I don't drink coffee or tea every day but only with I feel extra weak and it sure helps. Of course coffee can't replace Mestinon since there are other effects from too much coffee that I don't want, but a little coffee is great!