Sandra -

No time to read, must run. Don't have a problem with the premise of the paper, emphasis on "origin." What I do know is that if you go to the RSDSA Medical Artical Archieve page under "Research" http://www.rsds.org/2/library/articl....html#Research you'll get a number of articles showing a great drop off in the number of observed pro-inflammatory cytokines as CRSP begins it's transition to the chronic phase, where it is presumable maintained by ingrained permutations in the thamaic-cortical loops.

Is the problem of post-cytokine pain addressed in the paper to your knowledge?

Mike