Hi. I was recetnly diagnosed with MG. The diagnosis years in the making. Also have Lupus and Fibromyalgia. What a combo. I take Mestinon...Timespan int he morning along with 30mg of regular Mestinon. Then I take 30's latre afternoon, early evening, before I go to sleep. Better with the drug. Realy bad GI problems not all from Mestinon. I also take Cellcept. They all cam wreak havoc on your stomach. I feel like a prisoner in my home on most days. Imodium will allow me to get out. My eye lids always feel heaqvy as do my arms and legs. My speech can become impaired at the drop of a hat so I always carry mestinon with me and Ativan in jase I strt to get a panic attack. Any real physical activity and my breathing becomnes very labored. (another reason for the ativan to keep me calm) I've been trying really hard to keep working but I don't think I'll be able to continue. Anyone applied for Social Security Disability? So glad to have found this thread. Thanks everyone.