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Old 11-13-2009, 07:25 AM
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reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default forgot these

Regarding the neuroprotection, RLSmi correct me if I am wrong, but my understanding is that the low dose approach needs it to be there at the critical time in the early morning. That does not necessarily mean that its absence is required at other times. Also, a second protective action occurs in the damping down of the microglia which should be independent.

I'm avoiding the other ingredients to ward off unwanted effects. The plainer the better right now.

As for my "expertise".....


Quote:
Originally Posted by Conductor71 View Post
I have a few questions for those of you experimenting with DM:


-We're dosing based on finding that window for good symptom control- does this equate to or relate at all to the levels needed for neuroprotection?

In other words, neuroprotective benefit was found at femtomolar but not at picomolar levels. How in the world do we factor in this when dosing with a little plastic cup?

-I take it if the DM has guiafenesin or any other ingredient, it's not as efficacious? (I could initially only find DM with this additive)

-How does taking a supplement that has bioperine factor in? It's known to amp up meds in our system, I wonder if taking supplements might 'wash out' the potential neuroprotective benefit of DM?

Thank you so much for sharing your experiences and expertise!

Laura
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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