I had been taking 60mg every 6 hours but when I saw my neuro he told me he thought I needed to up it because I still have ptosis off and on and problems with my jaw being weak to the point where once in a while I feel like I am going to have to push it up to close my mouth. When he had me look up for 30 seconds my eyelid literally fell. He suggested going up to 90mg every 6 hours and work up to 120mg every 6 hours if I still had symptoms. I took the 90mg for a week and did better, then upped it to 120mg every 6 hours and that is definitely too much. There were days where by the time I took my 3rd dose my legs felt like Jell-O. As soon as the Mestinon wore off that went away. The last few days I am taking 90 mg 3 x a day. Today has been one of those days where I was fine until I took my afternoon dose and I was so weak in my legs and jaws I couldn't wait for it to wear off!!! It has now passed since I haven't had Mestinn since 12:30.