The Alpha Lipoic Acid puts upsets my stomach as well and puts me in left field big time to where I can't process. I tryed over and over to take it with food and other methods. Since ALA is such a robust chelator, I personally think it is trying to pull metal out that is stubborn and that is what's giving me the hard time. It really turns me into a vegetable, I have a serious (detox??)reaction every time I take it. In addition to it spiking my reflux. Ubiquinol can have a milder but similar effect after taking(I take this a couple times a week). I use GliSODin, Pomegranate, Selenium and Grape Seed extract as well as others like NAC, Curcumin and Holy Basil here and there. Starting to take Vitamin C again as well.