I saw a presentation about this at the 2003 (I think) PAN forum. The test subject had all his dyskinesia eliminated and his off-time significantly reduced. I think pill form is the worst way we can take our levodopa. The continuous, or hourly dosing with liquid sinemet seems to cause MUCH less in the way of side effects, dyskinesia and "off type"
such as bradykinesia and dystonia.

This is an understudied therapy, probably because it uses "off the self" technology.

Charlie