Daer CRPSbe,
Thanks for this very interesting link. Did you read about the study using intravenous magnesium?
Quote:
24.08.09 - Pilot study with magnesium promising
In a pilot study at the vu medical center in Amsterdam 8 patients received intravenous magnesium for 4 hours per day for 5 days.
The rationale behind this treatment is that CRPS is associated with an excessive inflammatory response. The resulting pain could lead to hypersensitivity of the nervous system (central or peripheral sensitisation. The activation of certain receptors (NMDA receptors) within the nervous system seems to play a key role in this process.
The researchers hypothesised that magnesium deactivates the NMDA receptors and as a result, diminishes the pain. Previous research showed that intravenous magnesium leads to a decrease in pain in both acute and chronic pain patients.
The results of this study showed that the pain had diminished significantly. The same was true of the general impairment level of the patients. The patients reported an improvement in the quality of life. However, no improvement was reported in functional impairments (like walking and sitting down) and the skin sensitivity was the same after the treatment as before it. An additional positive finding was that the patients reported only minor side effects.
On the whole the results of this pilot study are promising. The use of magnesium seems to be an effective treatment for CRPS 1. Further research is necessary.
Read about this study in:
Collins S, Zuurmond WW, de Lange JJ, van Hilten BJ, Perez RS. Invravenous Magnesium for Complex Regional Pain Syndrome Type I (CRPS 1) Patients: A Pilot Study. Pain Med 10:930-940.
[Abstract / Full text]
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Hope you are well.
MsL