Magnesium stearate in vitamins is not absorbed into the body.
It is inert. It is used as a "flow" improver so the powder will
come out of the hopper smoothly and into the tablet press properly, or fill a capsule properly.
If magnesium OXIDE appears on a label, very little of this is absorbed either... studies show 4%. To give a comparison, 3 oz of almonds have 270mg of magnesium! One cup of oatmeal has 57mg.
Here is a link with good information including RDA:
http://lpi.oregonstate.edu/infocente...ium/index.html
Multivits in general do not provide much magnesium if any.
The studies I have seen mentioning HIGH dose magnesium use in patients with MG involved IV mag sulfate given to women with MG who had eclampsia. (malignant hypertension of pregnancy).
I have not seen studies involving RDA levels of magnesium.
From 1990:
Quote:
Muscle Nerve. 1990 Aug;13(8):708-12.
Myasthenia gravis presenting as weakness after magnesium administration.
Bashuk RG, Krendel DA.
Emory University School of Medicine, Department of Neurology, Atlanta, Georgia.
We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia. The serum magnesium concentration was 3.0 mEq/L, which is usually well tolerated. The magnesium was stopped and she recovered over a few days. While she was weak, 2-Hz repetitive stimulation revealed a decrement without significant facilitation at rapid rates or after exercise, suggesting postsynaptic neuromuscular blockade. After her strength returned, repetitive stimulation was normal, but single fiber EMG revealed increased jitter and blocking. Her acetylcholine receptor antibody level was markedly elevated. Although paralysis after magnesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only manifestation of the disease. Patients who are unusually sensitive to the neuromuscular effects of magnesium should be suspected of having an underlying disorder of neuromuscular transmission.
PMID: 2385256 [PubMed - indexed for MEDLINE]
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and
Quote:
Obstet Gynecol. 1976 Jul;48(1 Suppl):35S-37S.
Myasthenia gravis and preeclampsia.
Cohen BA, London RS, Goldstein PJ.
Myasthenia gravis in pregnancy is rare, and its occurence in conjunction with preeclampsia has not been previously described. A case report of preeclampsia in a myasthenic patient is described with recommendations for management. The authors conclude that magnesium is a contraindicated pharmacologic agent in a myasthenic patient.
PMID: 940634 [PubMed - indexed for MEDLINE]
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We cannot live without magnesium. It is the HIGH dose sudden administration that appears in the literature as problematic.
Most doctors do not even know that magnesium oxide is useless. And I would not expect them to understand what is in a standard multivitamin either.
If you care to give me the brand I can look it up for you. But if it says magnesium stearate.... don't count on any absorption at all. Magnesium stearate is not soluble and melts at 88 C. It is a fatty waxy material not a significant source of magnesium. It appears on just about every Vitamin label, as inert ingredient.
two other sources:
http://www.absoluteastronomy.com/top...esium_stearate
and
http://www.raysahelian.com/magnesiumstearate.html
The commonest cause of high dose oral magnesium is Laxatives given to purge before tests. In fact Fleets Phospho Soda has been taken off the market. Enemas given too often by Fleets will also present significant problems.
edit to add.... it is not just vitamins that magnesium stearate is found.
Most RX drugs have it too. You can find the inert ingredients listed on the insert the pharmacy can give you that comes with the bottle, or on rxlist.com has many ingredients too.
Therapeutic amounts of magnesium are not in these dosage forms because that would create a HUGE pill...one that most people could not handle.
Here is the link to Mestinon:
http://www.rxlist.com/mestinon-drug.htm
Quote:
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Timespan Tablets containing 180 mg pyridostigmine bromide; each tablet also contains carnauba wax, corn-derived proteins, magnesium stearate, silica gel and tribasic calcium phosphate.
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Weezie looking at petunias 8.25.2017
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