What the heck is going on? WHY do researchers Ronald J. Mandel, PhD et al want to run a trial with GDNF for people with early stage Parkinson's only?

Why don't researchers set up three trials running concurrently?

1. early stage pd
2. middle stage pd
3. late stage pd

and then see what works for whom?!

And I agree that researchers will have a very hard time getting people with early stage pd to sign up for a gene therapy trial. If a person with early stage pd asked for my opinion, I would recommend against them taking the risk of brain surgery in any gene therapy trial.

I am outraged.