B2Y, I have a couple of down throws that measure 50 x 60 that I keep on our recliners during the winter. I machine wash them at least 2 times each winter. I have had no problem washing them in my top loading machine. I just keep them punched down while the water fills. To dry them I put a couple of tennis balls in the dryer to help fluff them back out.

If the ones you have are queen size... a commercial washer and dryer would be best.