Thanks mrsD. Yeah, I knew about the interaction warning with these two, but then again, it seems like most of the combinations folks here are taking are not really recommended. I wonder if this serotonin syndrome is something that would happen right away if you were prone to getting it or if it's something that could result from a cumulative effect.

Doses I'm currently taking: 60mg Cymbalta 1X a day and Ultram 50mg 6X a day. My neuro said that when using Cymbalta for PN, it's not usually effective until you're up to 90mg a day. So far I haven't noticed any effects at all, good or bad. I have found that my brain seems a lot clearer now that I'm not on 3600mg of Gabapentin, though.

Anyway, I wonder why he said that it would take a few months to help...but as I indicated before, my confidence level with this guy is not all that high.