LDN is not a mainstream DMD .... BUT it is ALSO not a mainstream symptom management drug for MS.

Naltrexone, at a much higher dosage, has been clinically trialed and on the market for many years ... for drug and alcohol abuse.

However, about 25 yrs ago (before the Disease Modifying Drugs were even on the market), a neurologist in New York got to thinking that it may work on MS .... at a much lower dosage. He started rxing to his patients for the purposes of reducing RELAPSES and disease PROGRESSION.

So ... those are the reasons that we take it ... and although this generic and cheap drug has never undergone clinical trials for MS, anecdotally many thousands of people take it with the goal to affecting the outcome of this disease. The fact that it works for symptoms as well, for many people, is just an added BONUS.

Pud's friend, I know of a handful of people who have gone off LDN. In most cases it is because they haven't seen the symptom improvement that they were hoping for ... so they lost faith that it might be working for the underlying disease process as well.

Cherie