Hi Peg,
How could you ever doubt me!!!! LOL
Your BBB ages like the rest of you!!! Eventually lets things in that it shouldn't.
This is why it is generally. an old person's disease. So stay young!!
You can get a damaged BBB by a blow to the head (Muhammed Ali),
So don't go and challenge Mike Tyson to 10 rounds.
You can damage your BBB by any of the sustances I list, such as pesticides.
Prolonged stress can increase permeabilty. So keep singing "Why worry"!!
If we can just get the permeabilities of PWP measured and get some correlation with permeability v length of duration of disease, we will be getting siomewhere. I am in contact with another Professor who is an expert in the field, and he has promised to look into it.
The measurement could be as standard as getting your cholesterol measured. If you monitored permeability, it would give early warning as to how close you are to the threshold, above which you start to show PD symptoms.
Ron