thanks, LInda, Lindy and Laura,

I am by no means in a place where i understand this. I'm trying to learn what it means as it sounds like significant changes are being made in research thinking, the nature of which, as it happened just by chance, i directly experienced upon taking aricept.

Had another thought. THey deliberately increase acetylcholine by inhibiting the inhibitor for alzheimers. So does that mean our own inhibitors, when not functioning or gone as they suggest, increase our acetylcholine? I can't quite grasp an understanding yet.

They are also working on a DBS for the PPN. I think Linda's remark about our current anticholinergics being adequate is a good question. I don't understand why we aren't all on an anticholinergic, although side effects occur and is it worth the risk?

paula