Quote:
Originally Posted by tysondouglass
Tomorrow is my flight back to North Carolina, sorta anxious about it, because i assume there will be cancellations, and delays due to snow which wont help the MG.
But im taking it hour by hour 
Lately, or every hour or so my eyelid, and eye spasms, which im not realy sure what that means, do any of you have that problem? I always have muscle spasms, i hate it. But it could be worse.
Why is the pred. not working on my eyelid? Im having a hard time keeping it open, and it sucks, and my breathing has gotten worse since ive been here, but not by alot.
Just confused to why after 3-4 weeks on the pred. why its not doing as much as people pray to.
Im having to take a nap everyday, and just overall really tired. Why is that?
The plasmapheresis isnt working as well as it did last time..
Hope you all had a great christmas! i did.
talk to you soon. |
the combination of mestinon and pred are designed to eleminate the effect of muscle weakness and failure on repeatability.
my neuro put me on a regime he new worked with other patients in the past.
I left the hospital on 60mgs per 24hrs of pred and 3*60mg per day of mestinon .
240mg day of drugs.
The pred did not kick in for 6 to 7 weeks.
therefore the only thing controlling the mg was mestinon at 180mg per day not 240mg of drugs needed.
I dont know the exact effect of pred relative to mestinon but say for talks sake it is 1mg pred is equivalent to 10mg mestinon then my initial dose equates to 60mg pred (600mg mestinon)and 180mg mestinon=total 780mg mestinon equivalent.
With the pred not working for 6-7 weeks during this time the only thing working is mestinon.
I had to increase my mestinon to 60mg every four hours =360mg mestinon
was not enough.
had to increase it to 120mg every four hours =720 mg .
better but not enough.
increased to 120mg every 3hours =8*120 960mg every 24 hrs
this proved too much giving eye and muscle twitch which are signs of overdose.
reduced it back to 7 *120mg =840mg mestinon no twitch no muscle spasms
good strenght all round and good repeatabillity ,no right eye pitosis.
now the pred kicks in and starts to work equivalent to 600mg mestinon(on my scale)
now we have mestinon equivalent 600(60mg pred)and 840mg mestinon total1440mg mestinon equivalent.
massive overdose relative to 780 required on leaving hospital.
THESE DRUGS CAUSE WEAKNESS IN OVERDOSE