Getting meds right is as big a challenge as raising teenagers. My problem is not exactly like yours but there are some similarities. I have had PD for about ten years. Four (or so) years ago I started with the curling toes and pain in the back of my legs. I had been taking Permax very successfully and the cramping and distortion started when I had to change meds.

The change to carba/leva did nothing to help. Ultimately I just kept taking more and more with no relief. Then Requip was started (again, the first time the nausea was more than I could live with) which allowed me to reduce much of the c/l but still did not help the problem enough to enjoy any q of l. Two weeks ago we added Amantadine. I'm up to two per day on my way to three and have had a marked improvement.

You never know if what works for one will work for another but maybe (?) Good luck,
PK