I used it a few months ago and posted a thread in which no one responded, metanx is a three combonatiom pharmautical vitamin with b6 b12 and folic acid , it is all natural so that the body will reconize and utilize all the nutriants, It is prescribed for nerve damage,,I tryed to use a combo of over the counter vitamins to mimic it,,it helps but the prescription does a better job,,,,,,,,,,