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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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Has anyone head of this flippin' study??
And 1992 at that!
1. Neurosci Lett. 1992 Oct 12;145(2):175-7.
Increased plasma concentrations of aspartate, glutamate and glycine in
Parkinson's disease.
Iwasaki Y, Ikeda K, Shiojima T, Kinoshita M.
Fourth Department of Internal Medicine, Toho University Ohashi Hospital, Tokyo,
Japan.
We measured fasting plasma amino acids in 20 patients with Parkinson's disease
(PD) and 20 controls matched for age and sex. PD patients had significant
elevations in plasma levels of aspartate, glutamate and glycine. The levels of
other amino acids were not significantly different from those found in controls.
No correlation was noted between PD severity and the degree of abnormality of
plasma amino acids. We conclude that excitatory amino acids may be altered in
patients with PD, and raise the possibility that neuroexcitotoxic mechanisms may
be involved in the neurodegeneration of PD.
PMID: 1361223 [PubMed - indexed for MEDLINE]
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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