I apologize for taking so long to write again. Thankyou so much for your advice to me earlier this month. Since I wrote about my horrible experience with severe neck pain and dyskinesia, right ankle swelling and tremors, I am still trying to figure out the best Stalevo dose for me. I think the ideal is somewhere between 100 and 125mg every 4 hours. Along with RequipXL 6mg and AZilect 1mg. It continues to be a struggle to figure out what dose is causing what symptom. Today I have had tremors, stiffness, transient neck pain,dykinesia of my feet. My muscles feel very tightly wound, even after getting a really good massage treatment yesterday. After all your input I realized that in November and December I started taking Actonel fror osteoporosis 150mg monthly for two doses. I found out that it can cause very debilitating neck spasms and muscle pain. So I am no longer on that and thank you Reverett for saying something HAD to have changed. All my neck pain is not gone but at least I can turn my head most days. And so I just want to say thanks again for reading my message and for all your helpful comments. This really is a great site, you are the best! FG