Thread: Bone Pain
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Old 01-24-2010, 12:12 AM
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Mslday Mslday is offline
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Hi Deb,

Here's a good description of the pathophysiology of bone pain from Wikipedia.

Quote:
The stimulation of the nociceptors that innervate bone tissue leads to the sensation of bone pain. Bone pain originates from both the periosteum and the bone marrow which relay nociceptive signals to the brain creating the sensation of pain. Bone tissue is innervated by both myelinated and unmyelinated sensory neurons (A-β, A-δ and C fibers). In combination, they can provide an initial burst of pain (myelinated neurons) followed by a slower and longer lasting dull pain (unmyelinated neurons).[5] [3]

Nociceptors responsible for bone pain can be activated via several mechanisms including deterioration of surrounding tissue, bone destruction[1], and physical stress which shears the bone, vascular, muscle, and nervous tissue.
There could be many reasons for bone pain, don't just chalk it up to RSD. As I understand it, it really depends on the what the cause of the bone pain is as to whether or not it would show on an MRI, neuropathic pain doesn't show up on an MRI. I've always had deep bone pain right from the beginning, more so than the burning. My recent MRI didn't show much so I was sent for a CT scan and just waiting on those results. Since you say that this is a new symptom for you you should probably consider having your doctor check you out.

Warm wishes

MsL
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fmichael (01-26-2010)