Both Effexor and Cymbalta are combo antidepressants.

They work on two neurotransmitters...norepi and serotonin.

They are called SNRI's not SSRI's.

The only difference I can see in pharmacology between the two is that Cymbalta can cause liver damage. Cymbalta is being heavily promoted by Lilly, hence all the doctors respond to the diabetic nerve studies that are presented to them. But the same doctors do not really understand or compare the drug to Effexor.

If someone does not do well on Effexor, they will most likely not do well on Cymbalta, and in addition are placing their liver at risk.

Some dementia symptoms in the elderly can be due to low B12.
http://www.aging-parents-and-elder-c...eficiency.html

A blood test of 400-500 minimum should be done. Anything lower than these numbers should be treated. Some doctors call 200-300 normal, still in this country with our antiquated lab ranges. So make sure any testing done, the results are actually given to you. Another test which shows if B12 is not working in the body is called an MMA test.
I have an informational B12 thread on this forum at the top of the page. This supplement is pennies a day when done carefully, and can have life changing results if the patient is low.