do you not take Mestinon at all? Pred and Cellcept are both long term repair options (immuno suppressants) and take a long time to do their thing (pred takes a year+ to improve things based on what I was told by the specialist I went to see). You should have *something* to treat the symptoms and get through the days. You also need to speak with your doc about the full run of plex not doing anything for you, that's really odd.