Does anyone know whether allergy shots interfere with the performance of Risperdal or other drugs used to treat bipolar children?

Our son was on Risperdal for ~18 months and was making great progress. He was able to go to kindergarten and 1st grade; he was making A's & B's; and his classroom behavior was similar to that of other young boys.

After an asthma attack in 10/05 put him in the hospital, he went back to school and his behavior continued to improve. In 12/05 we decided to give him allergy shots in an attempt to eliminate nasal congestion.

Almost immediately his classroom behavior began to get worse and his ability to concentrate on his school work went away. He also became more agitated and his manic episodes returned. In early 3/06 we took him out of the classroom environment and a school employee came to our home twice a week to help him with his school work.

In late 3/06 we replaced Risperdal with Geodon and his ability to concentrate returned and he finished the school year with all A's. His pleasant personality also returned without the manic episodes. The side effects of Geodon were that 1) his taste buds changed and he could not find any food that tasted good any more and 2) he had some involuntary physical movements (hopping and shoulder movements).

However, by June the positive effects of the Geodon had gone away and he became even more violent. In working with our psychiatrist we have tried various combinations of lithium, Geodon, Risperdal and Depokote. Nothing seems to bring his behavior back to where it was before the allergy shots. My wife is now home schooling him, but he has a lot of trouble concentrating even with all the one-on-one attention.

I have read that allergy medications such as Sudafed and St. John's wort should not be used with bipolar medications. Do you think allergy shots could cause problems that are similar to those caused by other allergy medications?

Looking for answers & ideas,

Fly2max