Hi franny,

That was another helpful piece of information! If you felt good on pamelor, you must be getting one of its intended purposes...regulation of acetylcholine. In this case, it is enabling the enzyme that breaks it down; so your cholinesterase dysfunction is translated into too much acetylcholine?? with parkinson's, it would respond well to the regulating of it and keeping it lower that nortiptyline enables, because now you also lack dopamine.

Complete speculation, but I think the questions are reasonable. keep in touch if you can franny....thank you for sharing your information. It's new to me.