For those of you who are considering taking testosterone as a replacement therapy, be careful because a study came out in 2006 from the Yale SOM that demonstrated high levels of exogenous testosterone kill brain cells. Ensure your doctor is giving you a physiological dose as opposed to a pharmaceutical dose, and make sure you get tests of your levels.

Also, a lot of physicians will prescribe DHEA concurrently with Testosterone. If yours does, be careful with this as well because it depletes cortisol levels, which is an important neurohormone. If you are supplementing DHEA, ensure that your adrenals are functioning correctly before hand and if they aren't, make sure they are getting the necessary support.